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Plesk + MailKite

Plesk is a popular web hosting control panel. Configure its mail server to relay through MailKite and every notification goes out over your own DKIM-signed domain.

What you need

Configure SMTP

Log into Plesk and navigate to Tools & Settings → Mail Server Settings. Under the SMTP Relay section, enable relay and enter the MailKite credentials.

SMTP Hostsmtp.mailkite.dev
SMTP Port587
EncryptionTLS (STARTTLS)
Usernamemailkite
PasswordYour API key (mk_live_…)
From Addresshello@yourdomain.com (on a verified domain)
Tools & Settings → Mail Server Settings
# Tools & Settings → Mail Server Settings → SMTP Relay

Enable SMTP relay: Yes
SMTP relay host: smtp.mailkite.dev
SMTP relay port: 587
SMTP relay username: mailkite
SMTP relay password: mk_live_...

Test it

Send email from a Plesk email account or use the Plesk mail test tool to verify outbound delivery through MailKite.

Troubleshooting

  • Emails not sending — confirm the From address is on a verified domain.
  • 535 Authentication failed — your password must be your mk_live_… API key, not a separate SMTP password.
  • Mail service disabled — ensure mail service is enabled for the domain. Go to Domains → yourdomain.com → Mail and verify it is active.

See the SMTP relay docs for the full connection reference, or all integrations for other platforms.